No email will be lost Thursday, May 28 2009 

This is to notify you of some additional work that needs to take place
to upgrade the Email and Calendar service. As a result of the work done
over the past weekend, most of the upgrade was completed uneventfully.
Due to an issue with hardware, we were unable to complete the entire
project in the time available without affecting other projects going on
over the weekend.

Because of this, we will be completing the upgrade on Friday, May 29th at
10:00 pm. We expect the work to be completed within 1 hour. During a
portion of this 1 hour period, several email servers will be unavailable
for approximately 40 minutes, including the server that processes your
email and calendar information. As that server is being upgraded, you
will be unable to download email, use Webmail, or use
the calendar. Your incoming mail will be queued and delivered
when the upgrade to the server is complete. No email will be lost.


Illumina Wednesday, May 20 2009 

Despite having nearly twice the number of markers, the Illumina 1M chip actually has substantially lower power than the earlier-generation 610K chip, for a simple reason: because the 1M chip is almost twice as expensive, researchers have to settle for genotyping many fewer individuals; and the increased power from adding more markers doesn’t make up for this drop in sample size.

classfied into two as Wednesday, May 20 2009 

Co-expressed genes are considered to be co-regulated which in turn considered to have common binding sites. The motif discovery algorithms can be classified into two as enumerative and probabilistic.

converge on Wednesday, May 20 2009 

Six police cars converged on the accident scene. ▪ Reporters from five different news sources converged on her after the game. Scholars from China, the United States and Canada will soon converge on Stanford’s East Asia Library to dissect the mysteries surrounding an ancient Chinese text.

Yoruba genome Wednesday, May 20 2009 

The two new sequences don’t reveal any genomic surprises. Researchers found approximately four million SNPs in the Yoruba genome, about 26 percent of which had not been previously identified. The Yoruba genome displayed a higher level of genetic diversity than previously sequenced single genomes, but earlier analysis of African DNA had predicted as much. The Chinese genome, in contrast, had about 13.6 percent previously unidentified SNPs.

interrogate Monday, May 18 2009 

We have continued to develop both the software infrastructure and tools for interrogating the stored data.

[+ obj] : to ask (someone) questions in a thorough and often forceful way interrogate a prisoner of war The suspect was interrogated (by the police) for several hours.

Lamarck Monday, May 18 2009 

This is a vindication of sorts for 18th century naturalist Jean Baptiste Lamarck. Lamarck, whose writings on evolution predated Charles Darwin’s, believed that evolution was driven in part by the inheritance of acquired traits.

With the advent of Mendelian genetics and the later discovery of DNA, Lamarck’s ideas fell out of favor entirely. Research on epigenetics, while yet to uncover anything as dramatic as Lamarck’s giraffes, does suggest that acquired traits can be heritable, and that Lamarck was not so wrong after all.

Concentrate on writing Monday, May 18 2009 


  1. Switch off email. I don’t start Outlook (or if I do, I disable all the notifications that tell me I have new mail).
  2. Isolate myself. I use Bose noise-canceling headphones but don’t plug them into anything. The silence really is golden.
  3. Greed and guilt. I remind myself how much money I’m getting paid for a particular assignment and how ashamed I will be if I miss the deadline. This actually works sometimes.
  4. Stop with the blog already. When I’m pressed for time, distractions like blogging and hoovering become very compelling. Knowing this makes it easier to resist.
  5. Get up early. 6am is the most productive time of day for writing. No distractions. It also feels more virtuous than staying up late with work.
  6. Little treats. I bribe myself: ‘Matthew, if you write another 500 words, you can have a cup of tea and a biscuit.’
  7. Chunking. Setting a timer or alarm clock for 15, 20, 30, 50 minutes and doing nothing but writing until it goes off and then taking a break seems like a good way to make progress.
  8. Go full screen. Switching Word into full screen mode (from the view menu) eliminates all distractions but the piece I’m working on.
  9. Shitty first draft. Splitting the work into distinct writing and editing phases breaks the job down nicely and it takes off some of the pressure to ‘get it right first time’.
  10. Change location. Sometimes, if I’m really struggling to get started, taking a laptop or my notebook to a cafe and scribbling out something there – a fresh new location – is a good way to jolt-start an assignment.

Two products:

Shanghai Surprise Saturday, May 16 2009 

The big three automakers are in crisis mode. All three screwed up to varying degree. [Chinese cars] are well-positioned to make the move (export to America). An established brand carries familiarity and comfort among consumers. Where some see crisis, others see opportunity. The fact is not a single gas-powered car assembled in the U.S. would meet China’s domestic standards.


debunk Thursday, May 14 2009 

contamination with modern human DNA is a serious concern, and so far 2 out of 4 existing studies have been effectively debunked.

[+ obj] : to show that something (such as a belief or theory) is not true : to show the falseness of (a story, idea, statement, etc.) The article debunks the notion that life exists on Mars. The results of the study debunk his theory.

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